Psychopharmacology Scavenger Hunt Concept Map
References
Berg, K. A., & Clarke, W. P. (2019). Making sense of pharmacology: Inverse agonism and functional selectivity. International Journal of Neuropsychopharmacology, 21(10), 962–977. https://doi.org/10.1093/ijnp/pyy071
Peris, L., & Szerman, N. (2021). Partial agonists and dual disorders: Focus on dual schizophrenia. Frontiers in Psychiatry, 12, 769623. https://doi.org/10.3389/fpsyt.2021.769623
Qin, J., Cai, Y., Xu, Z., Ming, Q., Ji, S.-Y., Wu, C., Zhang, H., Mao, C., Shen, D.-D., Hirata, K., Ma, Y., Yan, W., Zhang, Y., & Shao, Z. (2022). Molecular mechanism of agonism and inverse agonism in ghrelin receptor. Nature Communications, 13(1), 300. https://doi.org/10.1038/s41467-022-27975-9
Singam, E. R. A., Tachachartvanich, P., La Merrill, M. A., Smith, M. T., & Durkin, K. A. (2019). Structural dynamics of agonist and antagonist binding to the androgen receptor. The Journal of Physical Chemistry. B, 123(36), 7657–7666. https://doi.org/10.1021/acs.jpcb.9b05654
Vasan, S., Murray, B. P., & Olango, G. J. (2024, May 6). Amphetamine toxicity. StatPearls – NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK470276/
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Question
You will submit a concept map exploring the four agonists on the agonist spectrum (agonist, partial agonist, antagonist, and inverse agonist) in which you:
Describe the different characteristics of the four agonists and how each mediates distinct biological activities. Include proposed mechanisms and the receptor it is targeting.
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Psychopharmacology Scavenger Hunt Concept Map
Scavenge the literature after describing each agonist on the spectrum for research that is based on the medications in the table below.
Apply the medications to the appropriate agonist on the agonist spectrum in your Concept Map.
Medications
Oxycodone
Brexpiprazole
Haloperidol
Naloxone
Aripiprazole
Amphetamine
Risperidone
Pimavanserin
Follow the rubric and make sure you strive for the maximum points allowed based on the instructions AND the tool I will utilize to grade this concept map.