Peer Responses-ALTERATIONS IN CELLULAR PROCESSES

Peer Responses-ALTERATIONS IN CELLULAR PROCESSES

Responding to Anahita Yazdani

Hello Anahita,

This is a great post! I agree with you. Genetics make some individuals more susceptible to certain diseases, such as rhabdomyolysis. Your analysis of the disease provides clear insights into how several factors, such as genetics, the environment, and other personal characteristics, collectively predispose a person to health disorders. As you have presented, genetics is the major factor in the development of rhabdomyolysis. Besides genetics or family history, the development of rhabdomyolysis can be influenced by various factors, such as certain infections, drugs, exposure to toxins, and extreme exercise. Notable, having extreme exercises or suffering injuries with a risk of muscle trauma can also lead to the development of rhabdomyolysis. Prolonged immobilization has been noted to induce rhabdomyolysis (Seok et al., 2020) further. Rhabdomyolysis is also linked to the development of other diseases such as acute kidney injury with prolonged immobilization, especially in obese women (Sakai et al., 2020). This further shows how several factors, including genetics, gender, level of physical activity, and health status, can influence the development of health conditions.

References

Sakai, K., Omizo, H., Togashi, R., Hayama, Y., Ueno, M., Tomomitsu, Y., Nemoto, Y., Asakawa, S., Nagura, M., Arai, S., Yamazaki, O., Tamura, Y., Uchida, S., Shibata, S., & Fujigaki, Y. (2020). Rhabdomyolysis-induced acute kidney injury requiring hemodialysis after a prolonged immobilization at home in 2 morbidly obese women: Case reports with literature review. Renal Replacement Therapy, 6(1), 1–8. https://doi.org/10.1186/S41100-020-00277-W/TABLES/1

Seok, J. I., Lee, I. H., Ahn, K. S., Kang, G. W., Lee, J. W., & Kwak, S. (2020). Immobilization-induced rhabdomyolysis patients with peripheral neuropathy: clinical, laboratory and imaging findings. Annals of Clinical Neurophysiology, 22(1), 19–23. https://doi.org/10.14253/

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At its core, pathology is the study of disease. Diseases occur for many reasons. But some, such as cystic fibrosis and Parkinson’s Disease, occur because of alterations that prevent cells from functioning normally.

Understanding the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For the Advanced Practice Registered Nurse (APRN), this understanding can also help educate patients and guide them through their treatment plans.

For this Discussion, you examine a case study and explain the disease that is suggested. You examine the symptoms reported and explain the cells that are involved and potential alterations and impacts.

To prepare:

By Day 1 of this week, you will be assigned to a specific scenario for this Discussion. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.

Please post an explanation of the disease highlighted in the scenario provided. Include the following in your explanation -role genetics plays in the disease, why the patient is presenting with the specific symptoms described, physiologic response to the stimulus presented in the scenario and why you think this response occurred, the cells that are involved in this process, and how another characteristic like gender or genetics would change your response.