Common Respiratory Disorders
Asthma
Hereditary and environmental variables, including allergens, pollution, respiratory infections, and physical activity, can cause asthma, a chronic inflammatory disease of the airways. In asthma, pathophysiology includes inflammation of the airways, bronchial hyperresponsiveness, and overproduction of mucus, with resultant airflow obstruction (National Heart, Lung, and Blood Institute). It manifests as coughing, chest tightness, wheezing, and dyspnea, mainly at night or early morning: Common Respiratory Disorders.
Management includes trigger avoidance, bronchodilators such as albuterol for acute relief, and inhaled corticosteroids for long-term control. More severe cases may necessitate leukotriene modifiers or biologic therapies.
Chronic Obstructive Pulmonary Disease (COPD)
COPD is a progressive respiratory disease primarily caused by smoking, although factors such as air pollution and genetic predispositions, including alpha-1 antitrypsin deficiency, are also contributors. Diseases comprised in COPD are processes of emphysema involving alveolar destruction and chronic bronchitis, characterized by hypersecretion of mucus and inflammation of airways. These lead to narrowing the airspaces, loss of elastic lung recoil, and compromised gas exchange (Agarwal et al.).
The most important clinical manifestations include cough with chronic sputum production, dyspnea, and wheezing. Treatment includes smoking cessation, bronchodilators, corticosteroids, pulmonary rehabilitation, and oxygen in advanced disease.
Pneumonia
Pneumonia is an inflammation of the lung parenchyma brought on by bacterial, viral, or fungal infections, including Streptococcus pneumoniae. Risk factors include extremes of age, smoking, and immunosuppression. Pathologically, the alveoli get filled with fluid in this condition, which impairs gaseous exchange (Lim).
Manifestations include fever, chills, productive cough, dyspnea, chest pain, and fatigue. Treatment depends on the causative agent, including the administration of antibiotics for bacterial infections, antiviral medications for viral infections, and supportive therapy in terms of hydration and oxygen therapy.
Respiratory Infections
The most common cause of respiratory infections, such as influenza and the common cold, is viruses, though bacterial superinfections may complicate them. Pathogens invade the respiratory mucosa, inciting an inflammatory response with mucus secretion. Although the clinical symptoms might vary greatly, they frequently include fever, lethargy, coughing, runny nose, sore throat, and nasal congestion (Saleri and Ryan).
The treatment is usually supportive, with rest, fluids, antipyretics, and decongestants. Specific conditions, like influenza, may be treated with antiviral medication in an attempt to reduce symptom intensity and duration.
Works Cited
Agarwal, Anuj K., et al. “Chronic Obstructive Pulmonary Disease (COPD).” National Library of Medicine, StatPearls Publishing, 2023, www.ncbi.nlm.nih.gov/books/NBK559281/.
Lim, Wei Shen. “Pneumonia—Overview.” Reference Module in Biomedical Sciences, vol. 1, no. 1, Sept. 2021, pp. 185–197, https://doi.org/10.1016/b978-0-12-801238-3.11636-8.
National Heart, Lung, and Blood Institute. “What Is Asthma?” Www.nhlbi.nih.gov, National Heart, Lung, and Blood Institute, 17 Apr. 2024, www.nhlbi.nih.gov/health/asthma.
Saleri, Nuccia, and Edward T. Ryan. “Respiratory Infections.” Travel Medicine, 2019, pp. 527–537, https://doi.org/10.1016/b978-0-323-54696-6.00059-8.
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Discussion 3
Common Respiratory Disorders