Case Study and Discussion – Female Diagnosed with PCOS
Discuss 2 additional symptoms associated with PCOS in terms of pathophysiological principles.
In terms of pathophysiological principles, hirsutism and insulin resistance are two additional symptoms related to polycystic ovarian syndrome (PCOS). Hirsutism is characterized by excessive hair development in parts of the body where it is commonly seen in men, such as the face, chest, and back (Sachdev & Khunger, 2023). This is related to high amounts of androgens, such as testosterone, in PCOS patients. Many PCOS women also have insulin resistance, a condition in which the body’s cells do not respond adequately to insulin. As a result, insulin levels in the blood rise as the body compensates by manufacturing more insulin. Insulin resistance is linked to the metabolic elements of PCOS, such as obesity and a higher risk of type 2 diabetes.
How does Metformin contribute to treatment?
Metformin is a blood sugar-regulating drug commonly used in the treatment of PCOS. It can also help with PCOS-related infertility management by increasing insulin sensitivity and decreasing insulin resistance. Metformin may help restore more regular menstrual cycles and enhance the odds of ovulation, boosting the likelihood of pregnancy in certain women with PCOS by addressing these metabolic abnormalities.
How does progesterone aid in treatment?
Progesterone is frequently used to control menstrual cycles and improve fertility in the treatment of PCOS. Ovulation is frequently erratic or absent in PCOS, resulting in irregular or absent menstrual cycles (Chouhan, 2022). Progesterone can be administered to produce withdrawal bleeding, which mimics a natural monthly cycle and can help regulate the menstrual cycle and encourage regular ovulation, increasing the odds of conception.
How is infertility a symptom of PCOS?
Polycystic ovarian syndrome can lead to infertility because it alters a woman’s body’s normal hormonal balance. Women with PCOS frequently have increased androgen (male hormone) levels, which can result in irregular or nonexistent menstrual cycles. This hormonal imbalance can hinder the ovaries from producing eggs regularly, making it difficult for women with PCOS to conceive naturally and contributing to infertility.
References
Chouhan, A. S. (2022). Advance research on polycystic ovary syndrome (PCOS). Journal of Womens Healthcare & Midwifery Research, 1–5. https://doi.org/10.47363/jwhmr/2022(1)106
Sachdev, M., & Khunger, N. (2023). Essentials for aesthetic dermatology in ethnic skin: Practice and procedure. CRC Press.
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Question
Female Diagnosed with PCOS
Part 1: Choose a condition from the following case studies: (Week 5 Case Study Details).
Part 2: Select two different students/topics and discuss the condition encompassing clinical experiences and critique the post.
A 33-year-old obese female suffers from amenorrhea and infertility. After a thorough work up PCOS is diagnosed.
- Discuss 2 additional symptoms associated with PCOS in terms of pathophysiological principles.
- How does Metformin contribute to treatment?
- How does progesterone aid in treatment?
- How is infertility a symptom of PCOS?