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Multisystem Health Dysfunction

Multisystem Health Dysfunction

Musculoskeletal dysfunction is related to dysfunction in muscles, tendons, cartilage, joints, and nerves. The symptoms of musculoskeletal dysfunction, therefore, arise from these structures. These structures have different pathophysiological mechanisms leading to symptoms (Gómez-Galán et al., 2017). The symptoms seen in musculoskeletal disorders are usually a consequence of inflammation, infection, or trauma. The most common symptom of musculoskeletal dysfunction is a mismatch between the external load and the capacity of the body to withstand the load. External load is due to physical exertion and posture of the body. Other common symptoms include pain, swelling, muscle weakness, fatigue, stiffness, tenderness, and impaired function. Musculoskeletal dysfunction can affect patient function due to the impairment in the range of motion and movement of a patient.

Metabolic disorders are diseases that disrupt normal metabolism. These disorders can be either inherited or acquired. The inherited disorders can affect many different systems and are usually present according to the system that is affected. Gout, which is an inborn metabolic disorder, affects the musculoskeletal system (Hansildaar et al., 2020). It causes recurrent acute inflammatory attacks of the joints due to the deposition of uric acid salts. Variations in the SLC2A9 gene are associated with abnormal uric acid metabolism. This gene encodes for a protein that is involved in uric acid homeostasis. Arthritis due to gout also presents with pain and tenderness of the affected joint.

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Acquired disorders can sometimes occur together. The common symptoms that can be observed in a patient with acquired metabolic disorders include an increase in blood pressure, increased blood sugar levels, high cholesterol levels, and obese or overweight patients with excess body fat around the waist (Landrier et al., 2019). Being obese can affect one’s body function; they may develop musculoskeletal disorders due to excess weight applied to the joints. This impairs their movement.

Metabolic disorders increase the risk of developing organ dysfunction. Patients have to be wary of this by making the necessary adjustments to their diets and lifestyles. Metabolic disorders such as hypertension, gout, and diabetes affect patient function by increasing the risk of developing heart disease and stroke (Hansildaar et al., 2020). Diabetes can also cause peripheral neuropathy, especially in the lower limbs. This can result in loss of limb function.

References

Gómez-Galán, M., Pérez-Alonso, J., Callejón-Ferre, Á. J., & López-Martínez, J. (2017). Musculoskeletal disorders: OWAS review. Industrial Health, 55(4), 314-337.

Hansildaar, R., Vedder, D., Baniaamam, M., Tausche, A. K., Gerritsen, M., & Nurmohamed, M. T. (2020). Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout. The Lancet Rheumatology.

Landrier, J. F., Derghal, A., & Mounien, L. (2019). MicroRNAs in obesity and related metabolic disorders. Cells, 8(8), 859.

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Question 


Describe some of the more common pathophysiological changes and abnormal findings associated with musculoskeletal, metabolic, and multisystem health dysfunctions.

Multisystem Health Dysfunction

Multisystem Health Dysfunction

Explain what symptoms are associated with the findings and how these affect patient function.

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