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Infectious Disease- Syphilis

Infectious Disease- Syphilis

Syphilis is among the world’s highly contagious communicable diseases. The disease is caused by the bacterium Treponema pallidum (Satyaputra et al., 2021). Syphilis is majorly transmitted through sexual contact through the vagina, the anus, or through the mouth (World Health Organization, 2023). Besides transmission through sexual contact, it can also be transmitted from mother to child during pregnancy and the time of delivery. Get in touch with us at eminencepapers.com. We offer assignment help with high professionalism.

Symptoms

Syphilis develops from primary syphilis, secondary syphilis, and latent syphilis to tertiary syphilis (Satyaputra et al., 2021). Symptoms vary with the stage of progression. Primary syphilis is majorly manifested by painless canker sores or ulcers. The ulcer mainly develops at the site of infection, such as on the shaft of the penis, inside the vagina, or the rectum. The symptoms may be hard to notice and disappear. However, the infection remains active and progresses to secondary syphilis. The main symptoms of secondary syphilis include the appearance of a rash on any part of the body, such as around the vagina, anus, penis, hands or legs, a sore throat, painful swollen lymph nodes, and a persistent fever. Untreated syphilis then progresses to the latent stage. The latent stage of syphilis progression occurs over two years of untreated syphilis, and all of the previously manifested symptoms may disappear for years (Satyaputra et al., 2021). Syphilis then progresses to the tertiary stage, which is characterized by various multisystem complications that impact the patient’s daily living.

Complications

Untreated syphilis risks serious complications, including risks of heart and brain damage (World Health Organization, 2023). As a multisystem infection, syphilis affects other body organs, such as damage to the eyes, bones, liver, and critical organs, making it a life-threatening disease. Additionally, untreated maternal syphilis is linked to adverse birth outcomes (ABOs), including estimated stillbirths, preterm deliveries, low neonatal weight and deaths, and infected newborns (World Health Organization, 2023).

Treatment

Syphilis, as a bacteria-caused STI, is treatable using antibiotics. The major treatment option is the use of Benzathine penicillin. However, the dosage varies based on the stage in the progression of syphilis (Satyaputra et al., 2021).

Demographic Break Down of Syphilis

In the United States, syphilis incidence rates, prevalence, morbidity, and mortality vary across demographics. Prevalence is high among young adults between 20 to 29 years. Over six million cases of syphilis are reported annually across the population aged between 15 and 49 years (Satyaputra et al., 2021). Reported cases rose from 101,590 in 2017 to 171,074 in 2022 (Centers for Disease Control and Prevention (CDC), 2022). Data on syphilis incidences and prevalence from 2017 to 2021 showed that men were more affected by syphilis as compared to women (Centers for Disease Control and Prevention (CDC), 2022). Notably, 2019 data also shows that people of African American descent were at a higher risk of having syphilis than Whites. Although syphilis increases the risk of comorbid infections and complications, it is treatable and thus has a low mortality rate. Only 22 deaths were reported in the U.S. in 2019 (Centers for Disease Control and Prevention (CDC), 2022).

Determinants of Health

The HP2020 identifies various determinants of health for STIs. Syphilis is among the areas of focus in the prevention of STIs. The social determinants of health-related to syphilis, as per the HP2020, include the socioeconomic status of an individual, behavioral factors, lifestyle factors, the individual’s environment, and biology.

Having a lower socioeconomic status, such as a low level of education and living in poverty, increases the risk of developing syphilis as it determines access to care and a living environment. Engaging in risky behaviours and lifestyles, such as the use of drugs and unprotected sex with multiple sex partners, increases the risk of syphilis (Tapp & Hudson, 2020).

Social determinants related to the environment focus on the individual’s living environment. This is from the housing factors to the region of residence. Living in regions with high prevalence rates for syphilis increases the risk of contracting the STI, as observed in the current global trends (Ghanem et al., 2020).

An individual’s biological factors, such as genetics and immunity, can increase their risk of getting infected with STIs such as syphilis. Additionally, the accessibility and quality of available care is also a major determinant of health concerning syphilis. Improved access to quality syphilis care can prevent the progression of STIs and new infections.

On the other hand, poor quality of care and limited access to syphilis care services can lead to syphilis-related complications. Lack of access to quality care also increases the risk of transmission of the disease to other healthy individuals. These social determinants of health (SDH) contribute to the disparities in health outcomes related to syphilis (Johnson et al., 2022).

Epidemiological Triad

The development of syphilis and its prevalence and incident rates within the community are related to interactions between the factors related to the disease host, disease agent, and the environment. The host is the person infected with the disease. Various individual factors of the person, such as age, immunity, gender, and health status, determine how syphilis progresses and manifests itself across the various stages of development. Other factors, such behaviors and sexual orientation, can increase the risk of developing syphilis. For instance, gay and bisexual men have an increased risk of developing and spreading syphilis compared to individuals who are not gay or bisexual.

An agent is a microorganism responsible for the development of the STI. The agent for syphilis is the bacterium Treponema pallidum (Satyaputra et al., 2021). The progression, development, and community-level prevalence of syphilis depend on how the agent is controlled. Having access to quality care can detect syphilis in its early stages of development and eliminate the agent before it progresses to cause complications or lead to new infections. Poor management of the agent risks complications and the spread of syphilis across the population. Additionally, the environment, which is composed of all factors besides the host and the agent, is a critical factor for the community-level transmission of syphilis. Young people living in regions with higher prevalence rates and those who are sexually active with multiple partners risk new transmissions and infections.

Role of the NP

Nurse practitioners (NPs) have achieved the educational, training, and practice competencies to carry out various healthcare roles such as disease assessment, diagnosis, and treatment, as well as in the prevention and management of diseases (American Association of Nurse Practitioners (AANP), n.d.). NPs are involved in primary care and thus are the first point of contact between the population, patients, and the healthcare system. NPs, therefore, are essential healthcare professionals in the management of infectious diseases. As primary care providers, they can carry out epidemiological studies to survey and track the prevalence of a particular infectious disease, such as syphilis, at the community level. They also utilize available data and evidence to design and implement evidence-based primary, secondary, and tertiary interventions, including vaccinations, testing, awareness and treatment, and patient and population education. NPs also collect, analyze, synthesize, and report epidemiological data, which can be utilized in healthcare planning. Most importantly, NPs as primary care providers help assess patient needs at the point of care and utilize their expertise to improve disease management outcomes at the individual and community levels.

 References

American Association of Nurse Practitioners (AANP). (n.d.). What’s a Nurse Practitioner (NP)? Retrieved April 1, 2023, from https://www.aanp.org/about/all-about-nps/whats-a-nurse-practitioner

Centres for Disease Control and Prevention (CDC). (2022, September 1). Preliminary 2021 STD Surveillance Data. CDC. https://www.cdc.gov/std/statistics/2021/default.htm?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fstd%2Fstatistics%2F2020%2Fpreliminary2021.htm

Ghanem, K. G., Ram, S., & Rice, P. A. (2020). The Modern Epidemic of Syphilis. New England Journal of Medicine, 382(9), 845–854. https://doi.org/10.1056/NEJMRA1901593/SUPPL_FILE/NEJMRA1901593_DISCLOSURES.PDF

Johnson, K. A., Snyder, R. E., Tang, E. C., de Guzman, N. S., Plotzker, R. E., Murphy, R., & Jacobson, K. (2022). Geospatial Social Determinants of Health Correlate with Disparities in Syphilis and Congenital Syphilis Cases in California. Pathogens, 11(5), 547. https://doi.org/10.3390/PATHOGENS11050547/S1

Satyaputra, F., Hendry, S., Braddick, M., Sivabalan, P., & Norton, R. (2021). The Laboratory Diagnosis of Syphilis. Journal of Clinical Microbiology, 59(10), e0010021. https://doi.org/10.1128/JCM.00100-21/ASSET/3411773C-89BF-42EE-9D7B-39E3B2C74288/ASSETS/IMAGES/LARGE/JCM.00100-21-F001.JPG

Tapp, J., & Hudson, T. (2020). Sexually Transmitted Infections Prevalence in the United States and the Relationship to Social Determinants of Health. Nursing Clinics of North America, 55(3), 283–293. https://doi.org/10.1016/j.cnur.2020.05.001

World Health Organization. (2023). Syphilis. https://www.who.int/health-topics/syphilis#tab=tab_1.

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Question 


Week 5Infectious Disease Paper
Assignment

Pertussis, Rabies, or Syphilis
Purpose
Infectious disease occurs worldwide and must be addressed just as chronic disease is approached. This assignment will present the learner with an opportunity to explore a communicable disease, to apply the epidemiological triad, and discern the demographic and at-risk background data for a specific infectious disease agent.

Infectious Disease- Syphilis

Activity Learning Outcomes
Through this assessment, the student will meet the following Course Outcomes.
Identify appropriate outcome measures and study designs applicable to epidemiological sub-fields such as infectious disease, chronic disease, environmental exposures, reproductive health, and genetics. (CO3)
Identify important sources of epidemiological data. (CO6)

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